Abstract: An MRH-3 friction and wear tester was performed to evaluate the friction and wear behavior of flame-sprayed nylon1010 coating sliding against SAE52100 steel in a block-on-ring configuration, making use of uniform design method. The friction and wear test results were regression analyzed making use of Windows SPSS 11.0 statistics software. Thus a mathematical model was established to correlate the friction coefficient and wear mass loss of the coating with the PV value, while the worn surface morphologies of the coatings under different test conditions were observed on a scanning electron microscope. It was found that the regression formulae had prominence and statistical validity. The friction and wear behavior of the flame-sprayed nylon-1010 coating under different test conditions was closely related to the PV value, which was because the visco-elasticity of the coating varied with the variation of the sliding surface temperature. The nylon-1010 coating was dominated by elastic deformation at a smaller PV value which corresponded to a lower sliding surface temperature, thus the friction coefficient and wear mass loss were smaller in this case. The sliding surface temperature and damage increased with increasing PV value, thus the friction coefficient and wear mass loss increased aw well. At a high enough PV value, the sliding surface of the coating would experience local melting and form some kind of lubricating film, hence the friction coefficient and wear mass loss increased. The nylon-1010 coating was dominated by plastic deformation, fatigue, and adhesive wear.